LMIC News

Vitamin B12 reversed anxiety and depression induced by adolescent nicotine withdrawal through alteration the inflammatory, oxidative and serotoninergic profiles in male rats

Background: The present study aims to assess the effect of vitamin B12 (Vit B12) on depression-like behavior caused by nicotine (Nic) withdrawal, which is more likely due to the anxiogenic effect of Nic in adolescent male rats, through assessing behavioral and biochemical analysis.

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Development of Electrochemical Sensor Using Iron (III) Phthalocyanine/Gold Nanoparticle/Graphene Hybrid Film for Highly Selective Determination of Nicotine in Human Salivary Samples

Nicotine is the one of the major addictive substances; the overdose of nicotine (NIC) consumption causes increasing heart rate, blood pressure, stroke, lung cancer, and respiratory illnesses. In this study, we have developed a precise and sensitive electrochemical sensor for nicotine detection in saliva samples.

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Carcinogenic and non-carcinogenic health risk assessment of organic compounds and heavy metals in electronic cigarettes

E-cigarettes are now very popular in the world. Compared to traditional cigarettes, e-cigarettes are often considered safer and healthier. However, their safety remains controversial and requires further research and regulation. In this study, we aimed to understand the possible hazards to humans of four compounds (formaldehyde, acetaldehyde, acrolein, and acetone) and seven heavy metals (arsenic, cadmium, manganese, lead, copper, nickel, and chromium) contained in e-cigarette liquids and aerosols and perform a health risk assessment.

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Nicotine Transport across Calu-3 Cell Monolayer: Effect of Nicotine Salts and Flavored E-liquids

Objective: This study aimed to investigate the transport capability of nicotine across Calu-3 cell monolayer in various nicotine forms, including nicotine freebase, nicotine salts, and flavored e-liquids with nicotine benzoate.

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Terahertz label-free detection of nicotine-induced neural cell changes and the underlying mechanisms

Nicotine exposure can lead to neurological impairments and brain tumors, and a label-free and nondestructive detection technique is urgently required by the scientific community to assess the effects of nicotine on neural cells. Herein, a terahertz (THz) time-domain attenuated total reflection (TD-ATR) spectroscopy approach is reported, by which the effects of nicotine on normal and cancerous neural cells, i.e., HEB and U87 cells, are successfully investigated in a label/stain-free and nondestructive manner.

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Urine proteomic analysis of the rat e-cigarette model

Background: We were curious if the urinary proteome could reflect the effects of e-cigarettes on the organism.

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Tobacco harm reduction hearing Brazil - video submission

This is a contribution to a consultation and parliamentary deliberation held in Brazil in September 2023. I make five brief points in three minutes.

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THR Summit calls for alignment of communication to fight against misinformation

Delegates to the 6th Summit on Tobacco Harm Reduction (THR) have called for the alignment of communication to fight misinformation on THR, stressing that people need to get clear and strong messages about the scientific evidence on the benefits of harm reduction products in order to counteract the misinformation launched by opposing parts.

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