THR PubMed Research

Perceptions and Use of E-cigarettes among Young Adults with Cystic Fibrosis: An Observational Study

While smoking prevalence has decreased among the general population, the use of electronic cigarettes (E- cigarettes) has risen significantly and can cause significant lung injury.

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Trends of Single, Dual, and Polytobacco Use Among School-Based Students in the United States: An Analysis of the National Youth Tobacco Survey

To examine trends in single, dual, and polytobacco use between 2014-2020 for US youth and to identify disparities in these trends by grade level, sex, and race/ethnicity.

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Longitudinal Assessment of Association Between Tobacco Use and Tobacco Dependence Among Adults: Latent Class Analysis of the Population Assessment of Tobacco and Health Study Waves 1-4

With increasing tobacco product varieties, understanding tobacco use (TU) profiles and their associations with tobacco dependence (TD) has also become increasingly challenging.

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Comprehensive review of the national surveys that assess E-cigarette use domains among youth and adults in the United States

Surveillance of e-cigarette use among different population groups is important for the timely implementation and evaluation of tobacco regulatory policies.

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Effect of the nicotine replacement therapy on biomarkers of inflammation, endothelial dysfunction, oxidative stress and lipids in smokers who quit smoking

Our previous study showed major changes in biomarkers on quitting compared to the smoking state. They reflected a decrease of inflammation, endothelial activation, and oxidative stress, as well as an improved lipid profile.

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Effects of heated tobacco product aerosol extracts on DNA methylation and gene transcription in lung epithelial cells

Smoking causes DNA methylation (DNAm) alterations that lead to lung cancer development. Although the use of heated tobacco products (HTPs) has recently increased, their impact on health remains unclear. This study aimed to evaluate the effects of HTPs on DNAm and gene transcription in human lung epithelial cells in vitro.

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Dopamine D1-like receptor activation decreases nicotine intake in rats with short or long access to nicotine

The use of nicotine and tobacco products is highly addictive. The dopaminergic system plays a key role in the initiation and maintenance of nicotine intake.

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